"Dream, Dream, Dream! Conduct these dreams into thoughts, and then transform them into action."
- Dr. A. P. J. Abdul Kalam
17 Apr 2024
An Australian biotech entrepreneur and ophthalmologist outlines his vision for a day when a 3D printer and a little cell replication would be all that is needed to easily cure millions of blind people globally. Co-founder of Bienco, Professor Gerard Sutton asserts that the company currently has a physical and intellectual product that will enable it to mass-produce natural corneas for blind transplant recipients. The most popular method of recovering from blindness is cornea transplantation, however, this highly sophisticated process depends on donors. Damage or illness to the cornea, the thin, see-through "windscreen" of the eye, is a significant global cause of non-hereditary blindness.
Professor Sutton at work – credit Stefanie Zingsheim, University of Sydney
(Source; Google Images)
Insights from An Interview ~
Sutton's voice wanes during the conversation as he talks about his 2004 journey to Myanmar, where he trained doctors to conduct corneal transplants in an attempt to alleviate the country's blindness from the past civil war. He mentioned that he had four corneas from the NSW Eye Bank( Eye care center in Sydney, Australia) that he had brought with him. Thanks to a brief story in the local daily, wherein 1,000 people were waiting for him when he arrived at the clinic that was to welcome him. He had to choose four blind men and women out of a thousand, and he decided to give transplants to the young. This was a life-changing event, and after visiting Cambodia again, where a comparable circumstance occurred, Professor Sutton realized he had to take action—something "out of the field" that would enable him to donate as many corneas to these regions of the world as were required. One donor cornea is now available worldwide to treat every 70 individuals in need of a corneal transplant, according to Professor Damien Harkin, a member of Bienco's team stationed at the Queensland University of Technology."We estimate that a single donor cornea could treat thirty people through laboratory cultivation." Bienco’s artificial corneas are based on collagen, the proteins that make hair, skin, nails, and connective tissue. This tends to create opaque tissue, like our skin, and so the first challenge was to make collagen see-through.
After completing this step, Sutton and other Bienco members, including Harkin, faced the challenge of determining how to apply multiple layers of collagen to create a transplantable cornea structure.
In 2021, Sutton successfully persuaded the Medical Research Future Fund, established by the Australian Treasurer, to allocate AUD$35 million in support of Bienco.
With this substantial financial boost, Sutton anticipates that they are "three to four years away" from realizing their objectives and positioning Australia as a global hub for bioengineering.
Takeaway: Science As A Tool To Forge Ease Among the Lives of Special Needs ~
What Does Future Looks Like ~
(Source: Google Images)
An accidental discovery of a plant or microbial extract led to the development of early medications, which were then produced by trial and error testing of several chemicals to see which one worked best. With the aid of contemporary chemistry, scientists are now able to map the structures of pharmaceuticals, imitate their actions, and customize medications to meet the demands of each patient, making medical miracles a common occurrence.
It is anticipated that medical advancements will occur more swiftly, more effectively, and better, enabling patients to receive drugs more promptly. Since it will make healthcare services accessible to everybody, it will level the playing field. Age-related population growth and longer life expectancies create a huge need for better healthcare.
“Knowing is not enough; we must apply. Willing is not enough; we must do” ~ Johann Wolfgang von Goethe