"Dream, Dream, Dream! Conduct these dreams into thoughts, and then transform them into action."
- Dr. A. P. J. Abdul Kalam
22 Nov 2023
A groundbreaking device has been developed by scientists to uncover potential new medicines hidden beneath the sea. Marine organisms release countless invisible molecules into the ocean, and researchers believe that some of these compounds could hold the key to developing life-saving drugs.
The Mediterranean Institute of Marine and Continental Biodiversity and Ecology has successfully created a proof-of-concept device that can effectively "sniff" seawater, capturing and analyzing dissolved compounds. The device, known as the In Situ Marine moleculE Logger (I-SMEL), has shown promising results in underwater caves and delicate ecosystems like coral reefs.
Dr. Thierry Pérez, the co-author of the study, compared a drop of seawater to a complex broth of dissolved molecules from ocean-dwelling organisms. By isolating and examining these molecules, scientists hope to identify potential new natural products and unlock their medicinal properties.
The I-SMEL device, designed to be easily handled by underwater divers, uses specially designed disks to filter and enrich the dissolved compounds. In a recent test conducted in Mediterranean sea caves, the researchers discovered diverse elemental compositions and unknown molecular structures in the captured compounds.
This breakthrough opens up new possibilities for drug discovery, as several metabolites captured from seawater exhibited variations between different sponge species. These findings provide valuable insights into ecosystem health and offer the potential for developing innovative medicines.
The development of the I-SMEL device represents a non-invasive approach to studying marine environments and could lead to significant advancements in the field of pharmaceutical research. By tapping into the vast resources of the sea, scientists are hopeful that this device will uncover life-saving medicines that were previously hidden beneath the waves.